A laboratory studying glial cell biology and pathology in the central nervous system

Notes: left panel, confocal image showing myelin (MBP, red) and axons (SMI312, green) of 13 days old mouse spinal cord; middle panel, toluidine blue staining on the ventral white matter of adult mouse spinal cord (semithin section); right panel, transmission electron microscopic image of the corpus callosum of adult mouse brain. Copyright by the Guo Laboratory.

About us

The Guo laboratory is located at the 6th floor of Shriners Hospitals for Children, Northern California / UC Davis, Medical Center at Sacramento campus. Our research interest is glial cell biology and pathology (oligodendroglia, astroglia, microglia and ependymal cells) in the healthy and diseased CNS using a combination of genetic, molecular, cellular and high-throughput approaches applied to both in vitro and in vivo models.

Our lab currently receives funding from the NIH/NINDS and Shriners Hospitals for Children.

Link to Dep't of Neurology, UC Davis

Link to IPRM, Shriners hospital

Join the Lab

PhD/MD graduates interested in postdoctoral training: Contact the PI and send CVs (including publications and contacts of references).

The lab is recruiting postdoctoral researchers who are interested in studying biology and pathology of glial cells in healthy and diseased central nervous system. See the Job Posting

PhD and MD/PhD candidates interested in PhD training: Contact the PI and apply for the UC Davis Neuroscience Graduate Group or Integrative Pathobiology Group.

Lab staff or junior specialist positions: Contact the PI and send CVs

Research Funding

Shriners Hospitals for Children, 2023-2025

NIH/NINDS R01NS123165, 2022-2027

NIH/NINDS R21NS125464, 2022 - 2024

Shriners Hospitals for Children, 2022-2024

NIH/NINDS R01NS123080, 2021-2026

NIN/NINDS R01NS094559, 2016 -2022

Shriners Hospitals for Children #85107 2019 - 2022

NIH/NINDS R21NS109790, 2018 -2021

Shriners Hospitals for Children, 85200, 2016-2019

NIH/NINDS R21NS093559, 2016-2018

Shriners Hospitals for Children, 2015-2017

California Institute for Regenerative Medicine (CIRM) 2011-2014

Shriners Hospitals for Children 2008-2011