Publications

2023

Guo F and Wang Y (2023) TCF7l2, a nuclear marker that labels premyelinating oligodendrocytes and promotes oligodendroglial lineage progression. GLIA [PMID:35841271]  PDF version

2022

Wang Y, Zhang S, Lan Z, Doan V, Kim B, Liu S, Zhu M, Hull V, Rihani S, Zhang CL, Gray JA, Guo F (2022) SOX2 is essential for astrocyte maturation and its deletion leads to hyperactive behavior in mice. Cell Reports DOI: 10.1016/j.celrep.2022.111842 [PMID:36543123]

Wang Y, Sun B, Shitoba B, Guo F (2022) Transmission Electron Microscopic Analysis of Myelination in the Murine Central Nervous System. Cell Press: STAR Protocols Volume 3, Issue 2, 17 June 2022, 101304  (PDF) [PMID: 35496778]. 

Guo F, Zhang S (2022) Hypoxia inducible factor and diffuse white matter injury in the premature brain: perspectives from genetic studies in mice. Neural Reg. Res. 17(1):105-107. doi: 10.4103/1673-5374.314301 [PMID: 34100442]

2021

Wang Y, Guo F (2021) Group I PAKs in myelin formation and repair of the central nervous system: what, when, and how  Biological Reviews (doi: 10.1111/brv.12815) [PMID: 34811887]

Wang Y, Pleasure, D, Deng W, Guo F (2021) Therapeutic potentials of poly (ADP-ribose) polymerase 1 (PARP1) inhibition in multiple sclerosis and animal models: concept revisiting. Advanced Science doi: 10.1002/advs.202102853 [PMID:34935305]

Wang Y, Hull V, Sternbach, S, Popovich B, Burns T, McDonough J, Guo F, Pleasure D (2021) Ablating the transporter NaDC3 prevents leukodystrophy in Canavan disease mice. Ann Neurol 90(5):845-850 [PMID: 34498299]

Wang Y, Zhang Y, Zhang S, Kim B, Hull V, Xu J, Prabhu P, Gregory M, Martinez-Cerdeno V, Zhan X, Deng W, Guo F (2021) PARP1-mediated PARylation activity is essential for oligodendroglial differentiation and CNS myelination. Cell Reports 37(1):109695 [PMID: 34610310]

Zhang S, Wang Y, Zhu X, Song L, Ma E, McDonough J, Fu H, Cambi F, Grinspan J, Guo F (2021) The Wnt effector TCF7l2 promotes oligodendroglial differentiation by repressing autocrine BMP4-mediated signaling. J Neurosci. 41(8):1650-1664. doi: 10.1523/JNEUROSCI.2386-20.2021 [PMID: 33452226]

Zhang S, Wang Y, Xu J, Kim B, Deng W, and Guo F (2021) HIFα regulates developmental myelination independent of autocrine Wnt signaling. J Neurosci. doi: 10.1523/JNEUROSCI.0731-20.2020 [PMID: 33208471]

2020

Zhang S, Lan Z, Wang Y, Kim B,  Guo F (2020) The stem cell transcription factor SOX2 is essential for astrocyte maturation and controls animal hyperactive behavior. Research Square (Preprint), DOI: 10.21203/rs.3.rs-43277/v1

Zhang S, Wang Y, Kim B, Guo F (2020) A concept shift in the mechanistic understanding of HIFα-regulated developmental myelination. BioRxiv (preprint) doi: https://doi.org/10.1101/2020.03.30.015131 

Zhang S, Kim K, Zhu X, Gui X, Wang Y, Lan Z, Prabhu P, Fond K, Wang A, Guo F (2020) Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways. Nature Communications  doi: 10.1038/s41467-020-15656-4 [PMID:32332719]

Hao D, Fan Y, Xiao W, Liu R, Pivetti C, Walimbe T, Guo F, Zhang X, Farmer DL, Wang F, Panitch A, Lam KS, Wang A (2020) Rapid endothelialization of small diameter vascular grafts by a bioactive integrin-binding ligand specifically targeting endothelial progenitor cells and endothelial cells. Acta Biomaterial. doi: 10.1016/j.actbio.2020.03.005 [PMID: 32151698]

Hull V*, Wang Y*, Burns T, Zhang S, Sternbach S, McDonough J, Guo F, Pleasure D (2020) Antisense oligonucleotide reverses leukodystrophy in Canavan disease mice. Ann Neurol 87:480-485. doi: 10.1002/ana.25674 [PMID:31925837] (* co-first author).

2019

Clark K,  Zhang S, Barthe S, Kumar P, Pivetti C, Kreutzberg N, Reed C, Wang Y, Paxton Z, Farmer D, Guo F, Wang A (2019) Placental Mesenchymal Stem Cell-Derived Extracellular Vesicles Promote Myelin Regeneration in an Animal Model of Multiple Sclerosis. Cells 8 (12), 1497 

Hao D, He C, Ma B, Lankford L, Reynaga L, Farmer D, Guo F, Wang A (2019) Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus-Derived Mesenchymal Stem Cells for Fetal Tissue Engineering. Stem Cells Int. doi:10.1155/2019/9695239 [PMID: 31781252]

2018

Pleasure D, Guo F, Chechneva O, Bannerman P, McDonough J, Burns T, Wang Y, Hull V. (2018) Pathophysiology and Treatment of Canavan Disease Neurochemical research, 1-5

Zhang S, Rasai A, Wang Y, Xu J, Bannerman P, Erol D, Tsegaye D, Wang A, Soulika A, Zhan X, Guo F. (2018) The stem cell factor Sox2 is a positive timer of oligodendrocyte development in the postnatal murine spinal cord. Mol Neurobiol doi: 10.1007/s12035-018-1035-7 [PMID:29623612]

Zhang S, Zhu X, Gui X, Croteau C, Song L, Xu J, Wang A, Bannerman P, Guo F (2018). Sox2 is essential for oligodendroglial proliferation and differentiation during postnatal brain myelination and CNS remyelination. J Neurosci. doi: 10.1523/JNEUROSCI.1291-17.2018 [PMID:29335358]

Bannerman P*, Guo F*, Chechneva O, Burns T, Zhu X, Wang Y, Kim Bokyung, Singhal N, McDonough J, Pleasure D (2018). Brain Nat8l knockdown suppresses spongiform leukodystrophy in an aspartoacylase-deficient Canavan disease mouse model. Molecular Therapy 26:793–800 (* co-first author) [PMID:29456021].

2017

Hao D, Xiao W, Liu R, Kumar P, Li Y, Zhou P, Guo F, Farmer DL, Lam KS, Wang F, Wang A. (2017) Discovery and Characterization of a Potent and Specific Peptide Ligand Targeting Endothelial Progenitor Cells and Endothelial Cells for Tissue Regeneration. ACS Chem Biol. 2017 Apr 21;12(4):1075-1086.

Sohn J*, Bannerman P*, Guo F*, Burns T, Miers L, Croteau C, Singhal N, McDonough J, Pleasure D (2017). Suppressing N-acetyl-L-aspartate (NAA) synthesis prevents loss of neurons in a murine model of Canavan leukodystrophy (2017) J Neurosci 37:413-421 (* co-first author) [PMID: 2807779]

2016

Singhal NK, Huang H, Li S, Clements R, Gadd J, Daniels A, Kooijman EE, Bannerman P, Burns T, Guo F, Pleasure D, Freeman E, Shriver L, McDonough J. (2016)

The neuronal metabolite NAA regulates histone H3 methylation in oligodendrocytes and myelin lipid composition. Exp Brain Res. 2017 Jan;235(1):279-292. doi: 10.1007/s00221-016-4789-z. Epub 2016 Oct 5.

Tian Z, Guo F, Biswas S, Deng W. (2016) Rationale and methodology of reprogramming for generation of induced pluripotent stem cells and induced neural progenitor cells

Int J Mol Sci. 2016 Apr 20;17(4). pii: E594. doi: 10.3390/ijms17040594.

2015

Guo F, Lang J, Sohn J, Hammond B, Chang M, Pleasure D. (2015) Canonical Wnt signaling in the oligodendroglial lineage--puzzles remain. Glia doi: 10.1002/glia.22813 [PMID: 25782433].

Hammond E, Lang J, Maeda Y, Pleasure D, Angus-Hill M, Xu J, Horiuchi M, Deng W and Guo F (2015). The Wnt effector TCF7l2 positively regulates oligodendrocyte differentiation in a manner independent of Wnt/beta-catenin signaling. J Neurosci  35: 5007-22 [PMID: 25810530]

Guo F, Bannerman P, Mills Ko E, Miers L, Xu J, Burns T, Li S, Freeman E, McDonough JA, Pleasure D (2015). Ablating N-acetylaspartate prevents leukodystrophy in a Canavan disease model. Ann Neurol doi: 10.1002/ana.24392. [PMID: 25712859].

Sohn J, Orosco L, Guo F, Chung SH, Bannerman P, Mills Ko E, Zarbalis K, Deng W, Pleasure D (2015) The subventricular zone continues to generate corpus callosum and rostral migratory stream astroglia in normal adult mice. J Neurosci 35:3756-63. [PMID: 25740506].

He J, Hao S, Zhang H, Guo F, Huang L, Xiao X, He D (2015) Chronological protein synthesis in regenerating rat live. Electrophoresis. 36:1622-32. doi: 10.1002/elps.201500019. [PMID: 25873423].

2014

Moreno M, Bannerman P, Ma J, Guo F, Miers L, Soulika A, Pleasure D (2014) Conditional ablation of astroglial CCL2 suppresses CNS accumulation of m1 macrophages and preserves axons in mice with MOG peptide EAE. J Neurosci; 34, 8175-8185. [PMID: 24920622]

Ko EM, Ma J, Guo F, Miers L, Lee E, Bannerman P, Burns T,  Ko D,  Sohn J,  Soulika A, Pleasure D (2014) Deletion of astroglial CXCL10 delays clinical onset but does not affect progressive axon loss in a murine autoimmune multiple sclerosis model. J Neuroinflam 11, 105. [PMID: 24924222]

Chetty S, Friedman AR, Taravosh-Lahn K, Kirby ED, Mirescu C, Guo F, Krupik D, Nicholas A, Geraghty AC, Krishnamurthy A, Tsai MK, Covarrubias D, Wong AT, Francis DD, Sapolsky RM, Palmer TD, Pleasure D, Kaufer D (2014) Stress and glucocorticoids promote oligodendrogenesis in the adult hippocampus. Mol Psychiatry. 2014 Dec;19(12):1275-83. [PubMed PMID: 24514565].

Guo F, Ma JH, Pleasure DE. Encyclopedia of the Neurological Sciences. Second Edition ed. Aminoff MJ, Daroff RB, editors. USA: Elsevier; 2014. Chapter 172, Astrocytes (Neuroimmunology) (invited book chapter)

2013

Lang J, Maeda Y, Bannerman P, Xu J, Horiuchi M, Pleasure D, and Guo F (2013). Adenomatous Polyposis Coli Regulates Oligodendroglial Development. J Neurosci 33: 3113-30. [PMID: 23407966].

Moreno M, Guo F, Ko EM, Bannerman P, Soulika A, Pleasure D (2013). Origins and significance of astrogliosis in the multiple sclerosis model, MOG peptide EAE. J Neurol Sci 510x:638-7. [PMID: 23294494].

Chung SH, Guo F, Jiang P, Pleasure DE, Deng W (2013) Olig2/Plp-positive progenitor cells give rise to Bergmann glial in the cerebellum. Cell Death and Disease,  Mar 14;4:e546. doi: 10.1038/cddis.2013.7 [PMID: 23492777].

2012

Guo F, Maeda Y, Ko EM, Delgado M, Horiuchi M, Soulika A, Miers L, Burns T, Itoh T, Shen H, Lee E, Sohn J, Pleasure D (2012) Disruption of NMDA receptors in oligodendroglial lineage cells does not alter their susceptibility to EAE or their normal development. J Neurosci 32:639-45. [PMID: 22238099].

Sohn J, Selvaraj V, Wakayama K, Orosco L, Lee E, Crawford SE, Guo F, Lang J, Horiuchi M, Zarbalis K, Itoh T, Deng W, Pleasure D (2012) PEDF is a novel oligodendrogenic morphogen acting on the adult SVZ and corpus callosum.  J Neurosci. 32:12152-64. [PMID: 22933798].

2011

Guo F, Maeda Y, Ma J, Delgado M, Miers L, Ko EM, Bannerman P, Xu J, Wang Y, Zhou C, Takebayashi H, Pleasure D (2011) Macroglial plasticity and genetic origin of reactive astrocytes in experimental autoimmune encephalomyelitis.   J Neurosci 31:11914-28. [PMID: 21849552].

Wu Y, Guo F, Liu J, Xiao X, Huang L, He D (2011) Triple labeling with three thymidine analogs reveals a well-orchestrated regulation of hepatocyte proliferation during liver regeneration. Hepatol Res. 41:1230-9. [PMID: 21917088].

2010

Guo F, Maeda Y, Ma J, Xu J, Horiuchi M, Miers L, Vaccarino F, Pleasure D (2010) Pyramidal neurons are generated from oligodendroglial progenitor cells in adult piriform cortex. J Neurosci 30:12036-12049. [PMID: 20826667].

2009

Guo F, Ma J, McCauley E, Bannerman P, Pleasure D (2009) Early postnatal proteolipid promoter-expressing progenitors produce multilineage cells in vivo.  J Neurosci 29:7256-7270 [PMID: 19494148].

Before 2009

Zhang Z, Chen J, Guo F, He L, Wu Y, Zeng C, Xiao X, He D (2008) A high-temporal resolution technology for dynamic proteomic analysis based on 35S labeling. PLoS One. 20;3(8):e2991. [PMID: 18714357]

Guo F, Nian H, Zhang H, Huang L, Tang Y, Xiao X, He D (2006) Proteomic analysis of the transition from quiescent to proliferating stages in rat liver hepatectomy model. Proteomics 6:3075-3086 [PMID: 16619303].

Xiao X, Liu D, Tang Y, Guo F, Xia L, Liu J, He D (2003-2004) Development of proteomic patterns for detecting lung cancer. Dis Markers19(1):33-9 [PMID: 14757945].

Xiao X, Zhao X, Liu J, Guo F, Liu D, He D (2003) Discovery of laryngeal carcinoma by serum proteomic pattern analysis. Sci China C Life Sci. 47(3):219-23.[PMID:15524278].